Energy at the
cellular level.
NAD+ is a coenzyme central to how cells produce energy and repair DNA, and levels decline with age.
Supplementing it — by injection or infusion — supports mental clarity, physical recovery and the metabolic side of healthy ageing.
Benefits
Available as a quick subcutaneous injection or a slower IV infusion.
- Supports cellular energy production
- Improved mental clarity and focus
- Faster recovery after training
- Supports DNA repair pathways
- Complements peptide and hormone protocols
- Injection or infusion depending on your schedule
What Is NAD+ and Why Does It Decline With Age?
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every cell of the body, and it sits at the centre of two jobs that keep those cells running: converting the nutrients you eat into usable cellular energy, and supporting the processes cells use to repair DNA and regulate metabolism. Neither happens without it — which is why the age-related decline in NAD+ draws so much attention. Research suggests NAD+ levels fall substantially over a lifetime, with many estimates placing them at roughly half of young-adult levels by age 50. That decline is one plausible contributor to what people describe as feeling slower with age: lower energy that sleep does not fix, longer recovery after training, and a mental sharpness that takes more effort than it used to. It is worth being measured here — the science of NAD+ and ageing is active and still evolving, and supplementing NAD+ is intended to support the body's own cellular processes, not to reverse anything. What patients at Roots most often report is steadier energy, clearer focus and better recovery, which is consistent with what the coenzyme does rather than a promise of what it will do for any one person.
NAD+ Injections vs IV Infusions: Which Is Right for You?
Both deliver the same molecule — the difference is dose, pace and how they fit your schedule. IV infusions deliver a larger dose over a longer session, typically 30 to 60 minutes or more, run slowly because a fast drip can cause chest tightness or nausea. That higher dose is why infusions are often used to start a protocol or after a period of high demand. Injections are a quick subcutaneous shot — minutes, no IV line — carrying a smaller dose, which makes them the practical choice for regular maintenance once a protocol is established. In practice, many patients combine the two: an infusion or short series of them to begin, then injections every week or two to hold the level. Which one suits you depends on your goals, your labs and how much time you want to give each session, and it is decided with your provider at consultation rather than in advance.
Results vary and are not guaranteed. All treatments begin with a consultation.
Injection or IV — which is better?
Injections are fast and convenient for regular use. Infusions deliver a larger dose and are often used to start a protocol.
What does an infusion feel like?
NAD+ infusions are run slowly because a fast drip can cause chest tightness or nausea. Rate is adjusted for comfort.
How often?
Most protocols involve a loading phase, then maintenance every few weeks.
How do I know if NAD+ therapy is right for me?
The people who tend to do well with NAD+ therapy describe a similar picture: persistent fatigue that sleep has not resolved, a decline in mental clarity or focus, slower recovery after exercise, or an interest in supporting healthy ageing at the cellular level alongside a broader longevity plan. It is also common among patients already running a peptide or hormone protocol who want the metabolic side supported as well. That said, NAD+ is not automatically the answer for those symptoms — low energy has many causes, several of them more common than NAD+ decline, and treating the wrong one helps no one. That is why therapy at Roots starts with a consultation and bloodwork rather than an injection on the spot. Your provider looks at thyroid, metabolic markers, hormones and nutrient status first, and if the picture points to NAD+ it becomes part of a plan; if it points elsewhere, we treat what the labs actually show. Not everyone is a candidate, and a consult with the medical team is the starting point.
Can NAD+ therapy be combined with peptide or hormone therapy?
Yes, and at Roots that combination is common rather than exceptional. NAD+ supports the cellular-energy and metabolic pathways that peptide and hormone protocols also work through, so the three are frequently run together — for example, NAD+ alongside a growth-hormone-supporting peptide, or within a testosterone program where energy and recovery are part of the goal. Nothing is stacked blindly, though. Because these therapies share pathways, your provider designs them as one protocol rather than three separate ones: doses, timing and monitoring are coordinated, and follow-up labs confirm the combination is doing what it should. If you already take peptides or hormone therapy here, mention it at your NAD+ consultation and the plan will be built around it. If you are new to Roots, the initial labs and consult establish the full picture before anything is combined.
Thriving from the inside out.